Niggaz4Life, the final album by the legendary N.W.A was recorded in 1991 in the face of war and competition. After Dr. Dre, The D.O.C., and Michel’le bravely left Ruthless Records to become part of Death Row Records, things cooled off very quickly. There were reports that Eazy-E had been coerced into abandoning their contracts, though he held on to some of their publication rights. This paved the way for a "BEEF" between the former "Associates".

This rivalry began in 1992, when Death Row’s first single, "Fuck Wit Dre Day (And Everybody’s Celebratin’"), drew a character called "Sleazy-E" portrayed by the actor A.J. Johnson. In the clip, Sleazy came across as a hopeless man struggling to make ends meet. The feud raged on songs from Dr. Dre’s "The Chronic" such as the obscene "Bitches Ain’t Shit".

In 1993, Eazy-E hit back in a more aggressive attempt with his EP "It’s On (Dr. Dre) 187um Killa"with the HUGE Help of Gangsta Dresta and his Brother B.G Knocc Out, featuring heavy cuts such as "Real Muthaphuckkin G’s" and "It’s On". Eazy-E also attacked Dr. Dre’s reputable credibility, notoriously calling him a homosexual and mocking his new image when he called him and Snoop Dogg "studio gangsters". The video for "Real Muthaphuckkin G’s" featured a previously unknown photo of Dre wearing makeup and a sequined suit from his World Class Wreckin’ Cru days, when the style was in vogue among West Coast electro-hop artists, well before gangsta rap came along.

Tensions rose and Eazy-E continued to fire shots at Dre and Death Row until his death from complications of AIDS on 26 March 1995. Even MC Ren, Eazy-E's longtime friend, railed against Eazy-E in 1994 calling him a "big-head" and a "wannabe mega-star". They came back together shortly before Eazy-E’s death with their duet, "Tha Muthaphukkin’ Real," which was released two years later on the Eazy-E 's last Album "Str8 off tha Streetz of Muthaphukkin Compton".